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Asian Journal of Physics Vol. 33, Nos 9 & 10 (2024) 563-574

Medical diagnostics using gas in scattering media absorption spectroscopy GASMAS

Katarina Svanberg1,2 and Sune Svanberg3,2
1Division of Oncology, Department of Clinical Sciences, Lund University Hospital, SE-221 85 Lund, Sweden
2Lund Laser Center, Lund University, P.O. Box 118, SE-221 00 Lund, Sweden
3Department of Physics, Lund University, P.O. Box 118, SE-221 00 Lund, Sweden

Dedicated to Professor Anna Consortini for her significant contributions and pioneering works in the field of atmospheric turbulence and her continuous commitment to promote optics at global level 

Lasers, optical spectroscopy and imaging techniques provide many powerful approaches to fast, accurate and minimally invasive medical diagnostics. While most frequently broad-band spectroscopic techniques are used for tissue characterization, a new class of methods instead utilize narrow-band lasers for the monitoring of free gas in situ in the human body. The gas in scattering media absorption spectroscopy (GASMAS) technique relies on the fact that the absorptive imprints of free gases are typically 10,000 times narrower than those due to the tissue surrounding gas-filled vacuoles and cavities. Multiple scattering enhances the optical pathlength through the gas, but leaves absolute concentration assessments as a challenge. The GASMAS technique has many applications in food and fruit monitoring, as well as in studies of construction materials and pharmaceutical preparations. However, the present review will focus on emerging diagnostic techniques for common sinus and middle-ear infections (sinusitis and otitis), for surveillance of lungs, in particular for premature infants, and for studies of necrotizing bone structures. © Anita Publications. All rights reserved.
Doi: 10.54955/AJP.33.3-4.2024.287-306
Keywords: Biophotonics, Optics, Gas spectroscopy, Medical diagnostics, GASMAS technique.

Peer Review Information
Method: Single- anonymous; Screened for Plagiarism? Yes
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